The Cardiovascular Research Laboratory has, as one focus, the study of changes in cardiovascular function associated with healthy aging and age related diseases.
J. Andrew Taylor, PhD
Cardiovascular Health and Aging
The cardiovascular research program is focused on the study of changes in cardiovascular function associated with healthy aging and age related diseases. Current studies are investigating the mechanisms of these changes as well as interventions such as exercise and statin treatment to prevent or overcome cardiovascular declines associated with coronary artery disease, heart failure, and stroke.
The Cardiovascular Research Laboratory has, as one focus, the study of changes in cardiovascular function associated with healthy aging and age related diseases. Current researchis investigating the mechanisms of these changes as well as interventions such as exercise and statin treatment to prevent or overcome cardiovascular declines associated with aging, coronary artery disease, and heart failure.
Physiologic Basis of Post-TBI Symptoms
The Cardiovascular Research Laboratory is exploring potential deficits in the control of brain blood flow and/or the control of systemic pressure after traumatic brain injury (TBI) that may be responsible for symptoms (e.g., headache, dizziness) that can persist for up to a year after injury. In addition, anecdotal evidence suggests that exercise training reduces symptoms, but no controlled studies have been undertaken to determine the beneficial adaptations to exercise training that might reduce post-TBI symptoms. Therefore, part of this work is to explore the potential of an aerobic exercise training intervention for improving brain blood flow control and blood pressure control to resolve or reduce symptoms in post-TBI patients.
Cardiovacular Effects of Mind-Body Breathing
The Cardiovascular Research Laboratory has recently begun work to characterize the cardiovascular effects of an important common pathway for the effects of many mind-body interventions -- sustained, deep breathing. A fundamental component of many mind-body therapies is the regulation of breathing pattern; indeed, for some therapies, the regulation of breathing pattern is considered critical to its successful application. This may derive from the profound influence that breathing pattern exerts on the cardiovascular system. The overall aim of this work is to isolate and characterize the impact of breathing techniques common to mind-body medicine on cardiovascular control. Elucidating the mechanistic pathways by which breathing techniques impact specific physiological systems will greatly advance our understanding of mind-body medicine and potentially lead to clinically effective mind-body breathing interventions for populations with diseases characterized by cardiovascular deficits.
Spinal Cord Injury
Hybrid Functional Electrical Stimulation Exercise for SCI
The Cardiovascular Research Laboratory is collaborating with researchers in Oxford England who have developed a novel form of hybrid-fucntional electrical stimulation (FES) exercise. FES rowing for total body exercise in the SCI population involves simultaneous and coordinated engagement of both upper innervated and lower non-innervated limbs to produce an unique aerobic exercise for the SCI population. The work is distributed across a large muscle mass and produces high levels of sustained aerobic consumption. The focus of this work is to explore the potential of FES-assisted ergometer rowing for increasing cardiovascular health and function.
Click here for more information about functional electrical stimulation at Spaulding.
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